Cathepsin K Active from rat
SIGMA/SRP6559 - recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
Synonym: CTSK; CTSO; CTSO3
Product Type: Chemical
assay | ≥90% (SDS-PAGE) |
biological source | rat |
concentration | 0.5 mg/mL |
form | liquid |
mol wt | 23.5 kDa (115-329 aa) |
packaging | pkg of 5 μg |
pkg of 50 μg | |
recombinant | expressed in E. coli |
shipped in | dry ice |
storage temp. | −70°C |
UniProt accession no. | O35186 |
Biochem/physiol Actions: | Cathepsin K is a cysteine proteinase which is mainly responsible for osteoclastic bone matrix solubilization. It exhibits elastolytic as well as collagenolytic activities. |
General description: | Rat cathepsin K shares 88% identity with the human cathepsin K. It belongs to the papain superfamily and lysosomal protease family. The associated gene is strongly expressed in osteoclasts and osteoclastoma cells. |
Physical form: | 0.5 mg/mL solution in 25 mM Na2HPO4 and 500 mM NaCl (pH 7.0) with 50% glycerol. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥90% (SDS-PAGE) |
Storage Temp. | −70°C |
UNSPSC | 12352200 |