Wnt-2 human
SIGMA/SRP6560 - recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
Synonym: INT1L1; IRP; Int-1-like protein 1; Int-1-related protein
Product Type: Chemical
WNT Pathway Research areas: Developmental biology, Differentiation, Stem cell biology, Inflammation, Apoptosis, Autophagy Disease areas: Cancer, Parkinson’s disease, Diabetes, Familial Adenomatous Polyposis, Bone disease See also: SRP4754; SRP3296; SRP6560
Immunoblotting Wnt-2 Cat. No. SRP6560, SDS-PAGE (15%) of purified human recombinant Wnt-2. Lanes 1. MW Markers 2. rh WNT 2 (3 μg) 3. rh WNT 2 (6 μg) 4. rh WNT 2 (9 μg)
| assay | ≥90% (SDS-PAGE) |
| biological source | human |
| form | lyophilized |
| mol wt | 39.9 kDa |
| packaging | pkg of 1 mg |
| pkg of 10 μg | |
| pkg of 50 μg | |
| recombinant | expressed in E. coli |
| shipped in | wet ice |
| storage temp. | −20°C |
| UniProt accession no. | P09544   |
| Biochem/physiol Actions: | Wnt gene family members, including Wnt-1 through Wnt-10, play a key role in regulating cellular growth and differentiation. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt family member-2 (Wnt-2) has a role in activating β-catenin. It has been shown to have a role in cardiogenesis. The protein is overexpressed in tumors and cancers. |
| Physical form: | Lyophilized without additives. |
| Reconstitution: | Reconstitute in sterile ddH2O to a concentration ≥ 100 μg/mL. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥90% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |