Cathepsin K Active human
SIGMA/SRP6561 - recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
Synonym: CTSK; CTSO; CTSO3
Product Type: Chemical
Immunoblotting Cathepsin K Active Cat. No. SRP6561, SDS-PAGE (15%) of h-Cathepsin K. Lanes M. Protein Marker 1. Human Cathepsin K (5 μg) 2. Human Cathepsin K (10 μg) 3. Human Cathepsin K (15 μg)
| assay | ≥90% (SDS-PAGE) |
| biological source | human |
| concentration | 0.5 mg/mL |
| form | liquid |
| mol wt | 23.5 kDa (115-329 aa) |
| packaging | pkg of 5 μg |
| pkg of 50 μg | |
| recombinant | expressed in E. coli |
| shipped in | dry ice |
| storage temp. | −70°C |
| UniProt accession no. | P43235   |
| Biochem/physiol Actions: | Cathepsin K has a role in bone resorption and remodeling. It has a triple helical collagen hydrolase activity. Mutations in the gene encoding this protein have been linked to pycnodysostosis. |
| General description: | Cathepsin K is expressed as procathepsin K, which is the inactive proenzyme of cathepsin K. Cathepsin K is a lysosomal cysteine protease and part of the papain cysteine protease family. It is expressed in osteoclasts. The gene encoding this protein is localized on human chromosome 1q21. |
| Physical form: | 0.5 mg/mL solution in 25 mM Na2HPO4 and 500 mM NaCl (pH 7.0) with 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥90% (SDS-PAGE) |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |