CECR2 (424-538) GST tag human
SIGMA/SRP6578 - recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
Synonym: Cat Eye Syndrome Critical Region Protein 2
Product Type: Chemical
Immunoblotting CECR2 (424-538 aa) (GST-tagged) Cat. No. SRP6578, Human Recombinant CECR2 bromodomain. Lanes 1. Marker. 2. CECR2 (5 μg) 3. CECR2 (2.5 μg)
| assay | ≥95% (SDS-PAGE) |
| biological source | human |
| form | liquid |
| mol wt | 40.6 kDa (424-538 aa + NT GST Tag) |
| packaging | pkg of 20 and 100 μg |
| recombinant | expressed in E. coli |
| shipped in | dry ice |
| storage temp. | −70°C |
| UniProt accession no. | Q9BXF3   |
| General description: | The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as “readers” of histone acetylation marks regulating the transcription of target promoters. Cat eye syndrome critical region protein 2 (CECR2) is a transcription factor that forms a heterodimeric complex with the ATP-dependent chromatin remodeler SNF2L forming the CECR2-containing-remodeli |
| Physical form: | 50 mM Tris, pH 8.0, containing 150 mM sodium chloride and 20% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (SDS-PAGE) |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |