CD24 (mouse): FC (human)

SIGMA/SRP8027 - recombinant, expressed in HEK 293 cells, >90% (SDS-PAGE)

Synonym: M1/69-J11D heat stable antigen; NaMN adenylyltransferase 1; Nectadrin; X62 Heat stable antigen (HSA)

Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-SRP8027-50UG	50 µg	$589.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	>90% (SDS-PAGE)
biological source	mouse
form	lyophilized
impurities	<0.06 EU/μg endotoxin, tested
mol wt	~50 kDa by SDS-PAGE
packaging	pkg of 50 μg
recombinant	expressed in HEK 293 cells
shipped in	wet ice
storage temp.	−20°C
UniProt accession no.	P24807

General description:	CD24 is a highly glycosylated protein expressed as glycosyl-phosphatidyl-inositol (GPI) anchored molecule. Widely expressed, mainly on T cells, B cells and is upregulated in numerous types of cancers. It has costimulatory activity for antigen specific T cell responses. Polymorphisms of human CD24 are associated with several autoimmune diseases. Recently a new role as negative regulator of the immune response has been reported. CD24-deficient mice are more sensitive to inflammatory responses. CD24 together with the membrane protein SIGLEC interacts with danger-associated molecular patterns (DAMPs), such as HMGB1, HSP90 or HSP70. CD24/SIGLEC complex may differentially regulate the host response to DAMPs and PAMPs (pathogen-associated molecular patterns).
Other Notes:	Mouse CD24 (aa 27-52) is fused at the C-terminus to the Fc portion of human IgG1.
Physical form:	Lyophilized from PBS.
Reconstitution:	Reconstitute with 50 μL deionized water.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	>90% (SDS-PAGE)
Storage Temp.	−20°C
UNSPSC	12352200

Choose a favorite list for this item:

Catalog Number	Description	Price

		$

Please choose a list :

Continue Shopping

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.