IL-1 Receptor Type I (human): FC (human)
SIGMA/SRP8032 - recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)
Synonym: Interleukin-1 receptor alpha; Interleukin-1 receptor type I; RI; Serpin F1
Product Type: Chemical
assay | >95% (SDS-PAGE) |
biological source | human |
color | white |
form | lyophilized |
impurities | <0.1 EU/μg endotoxin, tested |
mol wt | ~80 kDa by SDS-PAGE |
packaging | pkg of 50 μg |
recombinant | expressed in HEK 293 cells |
shipped in | wet ice |
storage condition | avoid repeated freeze/thaw cycles |
storage temp. | −20°C |
UniProt accession no. | P14778 |
General description: | IL-1RI is the receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88, and IRAK1 or IRAK2. |
Other Notes: | Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused at the C-terminus to the Fc portion of human IgG1. |
Physical form: | Lyophilized from PBS. |
Reconstitution: | Reconstitute with 50 μL deionized water. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | >95% (SDS-PAGE) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |