CD40L, Soluble human
SIGMA/SRP8044 - recombinant, expressed in CHO cells, FLAG® tagged, >95% (SDS-PAGE)
Synonym: ACRP30headless:CD154; ACRP30headless:CD40L; ACRP30headless:TNFSF5; ADIPOQ-CD40L
Product Type: Chemical
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.
| assay | >95% (SDS-PAGE) |
| biological source | human |
| form | lyophilized |
| impurities | <0.01 EU/μg endotoxin, tested |
| mol wt | 35-40 kDa by SDS-PAGE |
| packaging | pkg of 10 μg |
| recombinant | expressed in CHO cells |
| shipped in | wet ice |
| storage condition | avoid repeated freeze/thaw cycles |
| storage temp. | −20°C |
| tag | FLAG® tagged |
| UniProt accession no. | P29965   |
| Biochem/physiol Actions: | CD40L (cluster of differentiation 40 ligand) is active in its membrane-bound form. It interacts with CD40 and functions as a proinflammatory and procoagulant agent. The serum levels of soluble CD40L is elevated in malignant middle cerebral artery infarction (MMCAI) patients, especially in non-surviving patients. |
| General description: | CD40L (cluster of differentiation 40 ligand) belongs to the tumor necrosis factor (TNF) family, and is expressed by basophils, B cells, monocytic cells, natural killer cells, platelets, mast cells and T cells. It is predominantly expressed on pro-inflammatory T cells. It also exists in a soluble form. |
| Legal Information: | FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Other Notes: | Human CD40L (aa 116-261) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag. |
| Physical form: | Lyophilized from PBS |
| Preparation Note: | Reconstitute with 100 μL deionized water. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | >95% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |