Netrin-1 (human): FC (human)
SIGMA/SRP8046 - recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)
Synonym: ACRP30headless:TNFSF13; NTN1
Product Type: Chemical
| assay | >95% (SDS-PAGE) |
| biological source | human |
| color | white |
| form | lyophilized |
| impurities | <0.1 EU/μg endotoxin, tested |
| mol wt | ~90 kDa by SDS-PAGE |
| packaging | pkg of 10 μg |
| recombinant | expressed in HEK 293 cells |
| shipped in | wet ice |
| storage condition | avoid repeated freeze/thaw cycles |
| storage temp. | −20°C |
| UniProt accession no. | O95631   |
| General description: | Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin 1 is also Involved in tumorigenesis by regulating apoptosis. |
| Other Notes: | Human netrin-1 (aa 25-604) is fused at the C-terminus to the Fc portion of human IgG1. |
| Physical form: | Lyophilized from PBS with trehalose and Brij35. |
| Reconstitution: | Reconstitute with 100 μL deionized water. |
| Hazard statements | H412 |
| Precautionary statements | P273 - P501 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | >95% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |