Omentin human
SIGMA/SRP8047 - recombinant, expressed in CHO cells, FLAG® tagged, >95% (SDS-PAGE)
Synonym: ACRP30headless:TNFSF13; Endothelial lectin HL-1; Galactofuranose-
CAS Number: 786735-12-4
Product Type: Chemical
| assay | >95% (SDS-PAGE) |
| biological source | human |
| color | white |
| form | lyophilized |
| impurities | <0.1 EU/μg endotoxin, tested |
| mol wt | ~38 kDa |
| packaging | pkg of 10 μg |
| recombinant | expressed in CHO cells |
| shipped in | wet ice |
| storage condition | avoid repeated freeze/thaw cycles |
| storage temp. | −20°C |
| tag | FLAG® tagged |
| technique(s) | ligand binding assay: suitable |
| UniProt accession no. | Q8WWA0   |
| Application: | Omentin (intelectin-1) has been used in intelectin binding and cleavage assays. |
| Biochem/physiol Actions: | Omentin (intelectin-1) has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. It increases protein kinase B (AKT) phosphorylation in the absence and presence of insulin. Omentin was suggested to play a role in the defense system against microorganisms by recognizing carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues. It has anti-inflammatory and insulin-sensitizing properties. The protein may be a biomarker of metabolic disorders. It has been shown to be over-expressed in human malignant pleural mesothelioma (MPM). |
| General description: | Omentin (intelectin-1) is highly expressed in omental adipose tissue, small intestine and various other tissues. It is a plasma adipokine made up of 313 amino acids. |
| Legal Information: | FLAG is a registered trademark of Sigma-Aldrich Co. LLC |
| Other Notes: | Human omentin (aa 17-313) is fused at the N-terminus to a FLAG®-tag. |
| Physical form: | Lyophilized from PBS. |
| Reconstitution: | Reconstitute with 100 μL deionized water. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | >95% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |