PEDF mouse
SIGMA/SRP8048 - recombinant, expressed in CHO cells, FLAG® tagged, >95% (SDS-PAGE)
Synonym: Caspin; PC cell-derived growth factor; Pigment epithelium-derived factor; Stromal cell-derived factor 3
CAS Number: 607410-75-3
Product Type: Chemical
| assay | >95% (SDS-PAGE) |
| biological source | mouse |
| color | white |
| form | lyophilized |
| impurities | <0.01 EU/μg endotoxin, tested |
| mol wt | ~47 kDa by SDS-PAGE |
| packaging | pkg of 10 μg |
| recombinant | expressed in CHO cells |
| shipped in | wet ice |
| storage condition | avoid repeated freeze/thaw cycles |
| storage temp. | −20°C |
| tag | FLAG® tagged |
| UniProt accession no. | P97298   |
| General description: | Pigment epithelium-derived factor (PEDF) is a 47kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells. |
| Legal Information: | FLAG is a registered trademark of Sigma-Aldrich Co. LLC |
| Other Notes: | Mouse PEDF (aa 20-417) is fused at the C-terminus to a FLAG®-tag. |
| Physical form: | Lyophilized from PBS. |
| Reconstitution: | Reconstitute with 100 μL deionized water. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | >95% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |