Periostin mouse
SIGMA/SRP8049 - recombinant, expressed in CHO cells, FLAG® tagged, >95% (SDS-PAGE)
Synonym: OSF-2; Osteoblast-specific factor 2; PC cell-derived growth factor
Product Type: Chemical
| assay | >95% (SDS-PAGE) |
| biological source | mouse |
| color | white |
| form | lyophilized |
| impurities | <0.1 EU/μg endotoxin, tested |
| mol wt | ~85 kDa |
| packaging | pkg of 10 μg |
| recombinant | expressed in CHO cells |
| shipped in | wet ice |
| storage condition | avoid repeated freeze/thaw cycles |
| storage temp. | −20°C |
| tag | FLAG® tagged |
| UniProt accession no. | Q62009   |
| Biochem/physiol Actions: | Periostin (POSTN) participates in collagen fibrillogenesis. It plays a major role in the development of scar after traumatic spinal cord injury (SCI). Periostin controls the activities of fibrocyte to stimulate myofibroblast differentiation and lung fibrosis. It modulates the amount of collagen in tissue. Periostin also participates in the assembly of the extracellular matrix (ECM) architecture. |
| General description: | Periostin (POSTN) is also called as osteoblast-specific factor 2. It is a matricellular protein, located in the alveolar walls. This gene is located on human chromosome 13q13. |
| General description: | Periostin was originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta1 (TGF-beta1) and bone morphogenetic protein (BMP-2). Abnormal expression of periostin is also linked to angiogenesis and metastasis in epithelial tumors. |
| Legal Information: | FLAG is a registered trademark of Sigma-Aldrich Co. LLC |
| Other Notes: | Mouse periostin (aa 24-783) (isoform 5) is fused at the C-terminus to a FLAG®-tag. |
| Physical form: | Lyophilized from PBS. |
| Reconstitution: | Reconstitute with 100 μL deionized water. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | >95% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |