D-(+)-Trehalose dihydrate
SIGMA/T0167 - from Saccharomyces cerevisiae, powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥99%
Synonym: α,α-Trehalose; α-D-Glucopyranosyl-α-D-glucopyranoside
CAS Number: 6138-23-4
Empirical Formula (Hill Notation): C12H22O11 · 2H2O
Molecular Weight: 378.33
EC Number: 202-739-6
MDL Number: MFCD00071594
Linear Formula: C12H22O11 · 2H2O
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T0167-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T0167-10G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T0167-25G
| assay | ≥99% |
| biological source | Saccharomyces cerevisiae |
| form | powder |
| InChI | 1S/C12H22O11.2H2O/c13-1-3 |
| InChI key | DPVHGFAJLZWDOC-PVXXTIHASA |
| product line | BioReagent |
| Quality Level | 200  |
| SMILES string | [H]O[H].[H]O[H].OC[C@H]1O |
| solubility | H2O: 50 mg/mL |
| technique(s) | cell culture | insect: suitable |
| cell culture | mammalian: suitable |
| Application: | D-(+)-Trehalose dihydrate has been used in a slow-freezing method for freezing rabbit oocytes. It has also been used in solid-surface vitrification (SSV) of in vitro-matured oocytes. It is suitable for use as a cryoprotectant in a variety of cell freezing media. |
| Biochem/physiol Actions: | Trehalose is essential for embryogenesis, carbon metabolism, photosynthesis and flowering in plants. It predominantly exists among the species that supports anhydrobiosis (life without water). It serves as a carbohydrate reserve in microorganisms and protects them from adverse conditions, such as heat, cold, dehydration, desiccation and oxidation. Trehalose acts as a chemical chaperone affecting protein folding. It is known to prevent amyloid generation and accummulation of β-amyloid in vitro. A similar effect of trehalose has been observed with huntingtin protein aggregation. Thus, it might serve as a protective agent in Alzheimer′s disease and Huntington′s disease. |
| General description: | Trehalose is a non-reducing disaccharide, ubiquitously present in nature. It is used as a food preservative and also to retain enzymes, vaccines, cells and many other molecules. Trehalose is present as hemolymph sugar among the invertebrates. |
| Packaging: | 10, 25, 100 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% |
| UNSPSC | 12352201 |