Tau-381 human
SIGMA/T0201 - recombinant, expressed in E. coli, ≥90% (SDS-PAGE), lyophilized powder
MDL Number: MFCD07785731
Product Type: Chemical
| application(s) | cell analysis |
| assay | ≥90% (SDS-PAGE) |
| biological source | human |
| form | lyophilized powder |
| mol wt | 39.7 kDa |
| Quality Level | 200  |
| recombinant | expressed in E. coli |
| shipped in | wet ice |
| storage temp. | −20°C |
| UniProt accession no. | P10636  |
| Biochem/physiol Actions: | Isoform of Tau, variant 1N3R, having 3 microtubule binding repeats (R) and one amino terminal insert (N). |
| Biochem/physiol Actions: | Microtubule associated protein tau (MAPT) aids in the assembly and maintenance of microtubule structure. Loss of expression of MAPT results in developmental delay and learning disability. The protein has been associated with pathology of Alzheimer′s disease (AD). |
| General description: | The gene microtubule associated protein tau (MAPT) is localized on human chromosome 17q21.3. It is expressed in neurons, more specifically in axons. |
| Reconstitution: | Lyophilized from MES, pH 6.8, containing NaCl and EGTA. When reconstituted in water to a protein concentration of 1 mg/mL, the resulting buffer will have ~50 mM MES, pH 6.8, 100 mM NaCl, and 0.5 mM EGTA. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥90% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |