Thymine

SIGMA/T0376 - ≥99%

Synonym: 2,4-Dihydroxy-5-methylpyrimidine; 5-Methyluracil

CAS Number: 65-71-4
Empirical Formula (Hill Notation): C₅H₆N₂O₂
Molecular Weight: 126.11
EC Number: 200-616-1
MDL Number: MFCD00006026
Linear Formula: C₅H₆N₂O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-T0376-5G	5 g	$60.50 1/EA		Add To Favorites
45-T0376-10G	10 g	$69.10 1/EA		Add To Favorites
45-T0376-25G	25 g	$75.60 1/EA		Add To Favorites
45-T0376-100G	100 g	$212.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥99%
InChI	1S/C5H6N2O2/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)
InChI key	RWQNBRDOKXIBIV-UHFFFAOYSA-N
mp	~320 °C (dec.) (lit.)
Quality Level	200
SMILES string	CC1=CNC(=O)NC1=O

Application:	Thymine has been used as a standard nitrogenous base in high-performance liquid chromatography-ultraviolet (HPLC-UV) for the quantification of bone DNA samples, Raman scattering experiments. It has also been used as supplement in C2C12 myoblast cells. Thymine may be used to study chemical processes that affect DNA structure, such a radiation induced radical production leading to base cross-linking reactions and derivitizations. It may be used to study the parameters of hydrogen bonding kinetics and energies with other nucleobases such as adenine.Thymine is used to develop sensitive heavy metal (mercury) detectors based on coordination chemistry and nanoparticle structures.
Biochem/physiol Actions:	Thymine used in studying DNA structure byirradtaion methods leading to cross-linking reactions and derivitizations. Thymine dimers are indicative of DNA damage. Thymine is used with metal (mercury) to form thymine−HgII−thymine (T−HgII−T) duplexes. Thymine starvation in bacteria leads to halt in DNA synthesis and is referred as thymine-less death.
General description:	Thymine is one of the four nucleobases, along with adenine, guanine and cytosine found in deoxyribonucleic acids (DNA).
Packaging:	5, 10, 25, 100 g in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99%
mp	~320 °C (dec.) (lit.)
UNSPSC	41106305

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