Synonym: 3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine sodium salt; Sodium levothyroxine; T4
CAS Number: 6106-07-6
Empirical Formula (Hill Notation): C15H10I4NNaO4 · 5H2O
Molecular Weight: 888.93
EC Number: 200-221-4
MDL Number: MFCD00149110
Linear Formula: HOC6H2I2OC6H2I2CH2CH(NH2)COONa · 5H2O
Product Type: Chemical
assay |
≥98% |
biological source |
synthetic (organic) |
form |
powder |
InChI |
1S/C15H11I4NO4.Na.5H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;;;;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;5*1H2/q;+1;;;;;/p-1/t12-;;;;;;/m0....../s1 |
InChI key |
JMHCCAYJTTWMCX-QWPJCUCISA-M |
mp |
207-210 (dec.) (lit.) |
potency |
5-50 ng/mL |
product line |
BioXtra |
Quality Level |
200 |
SMILES string |
O.O.O.O.O.[Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O |
solubility |
cell culture medium: 0.1 mg/mL |
|
H2O: soluble |
sterility |
γ-irradiated |
storage temp. |
−20°C |
technique(s) |
cell culture | mammalian: suitable |
Biochem/physiol Actions: |
L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis. |
Physical form: |
powder-0 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw, solution stable 2-8 °C, 30 days |
Reconstitution: |
To prepare 20 μg/ml stock solution, add 50 ml sterile culture medium. |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥98% |
mp |
207-210 (dec.) (lit.) |
Storage Temp. |
−20°C |
UNSPSC |
12352200 |