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D-α-Tocotrienol

SIGMA/T0452 - from rice, ≥75% (GC)

Synonym: 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2H-1-benzopyran-6-ol

CAS Number: 1721-51-3
Empirical Formula (Hill Notation): C29H44O2
Molecular Weight: 424.66
Linear Formula: C29H44O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-T0452-10MG 10 mg
 $434.00
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assay ≥75% (GC)
biological source rice
color colorless to brown
form liquid
InChI 1S/C29H44O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h12,14,16,30H,9-11,13,15,17-19H2,1-8H3/b21-14+,22-16+/t29-/m1/s1
InChI key RZFHLOLGZPDCHJ-XZXLULOTSA-N
mp 30-31 °C
Quality Level 200 
SMILES string O1[C@@](CCc2c1c(c(c(c2C)O)C)C)(CCC=C(CCC=C(CCC=C(C)C)/C)/C)C
storage temp. −20°C
Biochem/physiol Actions: α-Tocotrienol may be used along with other isoforms to differentiate tocotrienol activities.
Biochem/physiol Actions: Tocotrienols are widely utilized for their strong antioxidant properties. The various isoforms of tocotrienols differ in their methyl substitution in the chromanol head. α-tocotrienol demonstrates neuroprotective properties by blocking glutamate-induced cell death in neuronal cells.
Biochem/physiol Actions: α-Tocotrienol is an effective free radical scavengerand elicits protective functionality during oxidative stress in microsomes. It is a strong antioxidant, which reduces inflammation and is used in cancer treatment. α-tocotrienol supplementation may reduce cholesterol levels in hypercholesterolemia. α-tocotrienol is neuroprotective as it blocks glutamate-induced cell death in neuronal cells.
General description: Tocotrienols belong to the vitamin E family and have an unsaturated isoprenoid side chain. The various isoforms of tocotrienols differ in their methyl substitution in the chromanol head. α-Tocotrienol present in crude palm oil is regarded as a natural supplement.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥75% (GC)
mp 30-31 °C
Storage Temp. −20°C
UNSPSC 12352205

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