D-δ-Tocotrienol
SIGMA/T0577 - from rice, ≥65% (GC)
Synonym: (R-
CAS Number: 25612-59-3
Empirical Formula (Hill Notation): C27H40O2
Molecular Weight: 396.61
Linear Formula: C27H40O2
Product Type: Chemical
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| biological source | rice |
| color | yellow to orange |
| concentration | ≥65% (GC) |
| form | liquid |
| InChI | 1S/C27H40O2/c1-20(2)10-7- |
| InChI key | ODADKLYLWWCHNB-LDYBVBFYSA |
| Quality Level | 100  |
| SMILES string | O1[C@@](CCc2c1c(cc(c2)O)C |
| storage temp. | −20°C |
| Biochem/physiol Actions: | D-δ-Tocotrienol suppresses ras sarcoma (Ras) protein levels. It elicits anti-proliferative functionality in melanoma cells by halting cell cycle and favoring apoptosis. δ-Tocotrienol is cytotoxic to human lung adenocarcinoma and glioblastoma cancer cells. δ-Tocotrienol possesses anti-inflammatory, antidiabetic and neuroprotective functionality. It is an effective hypocholesterolemic agent and an inhibitor of lipid peroxidation. |
| Biochem/physiol Actions: | Tocotrienols are widely utilized for their strong antioxidant properties. The various isoforms of tocotrienols differ in their methyl substitution in the chromanol head. δ-tocotrienol, effectively blocks cleavage of SREBPs, ultimately decreasing the amount of cholesterol synthesized in the liver. |
| General description: | D-δ-Tocotrienol is a bioavailable isomer of vitamin E and has farnesyl side chain. Palm oil is rich in δ-Tocotrienol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352205 |