Teicoplanin
SIGMA/T0578
Synonym: Targocid; Teichomycin
CAS Number: 61036-62-2
Product Type: Chemical
| antibiotic activity spectrum | Gram-positive bacteria |
| assay | ≥80% (teicoplanins A2, HPLC) |
| color | white to faint beige |
| white to faint yellow | |
| white to light brown | |
| form | powder |
| InChI | 1S/C88H97Cl2N9O33/c1-3-4- |
| InChI key | BJNLLBUOHPVGFT-QRZIFLFXSA |
| mode of action | cell wall synthesis | interferes |
| Quality Level | 200  |
| storage condition | (Keep container tightly closed in a dry and well-ventilated place.) |
| storage temp. | 2-8°C |
| Application: | Teicoplanin is a glycopeptide antibiotic produced by Actinoplanes teichomiceticus that is effective against Gram-positive bacteria resistant to β-lactam antibiotics. Teicoplanin and vancomycin have been used clinically for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections. Product T0578 is a mixture of six primary teicoplanins; primarily teicoplanins A2 group. |
| Biochem/physiol Actions: | Teicoplanin is a glycopeptide antibiotic produced by Actinoplanes teichomiceticus that is effective against Gram-positive bacteria resistant to β-lactam antibiotics. Its mechanism of action is through inhibition of bacterial cell wall biosynthesis. Teicoplanin and vancomycin have been used clinically for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections. |
| Biochem/physiol Actions: | Teicoplanin is a glycopeptide antibiotic. It is a mixture of several compounds, five major (named teicoplanin A2-1 through A2-5) and four minor (named teicoplanin RS-1 through RS-4). All teicoplanins share a same glycopeptide core, termed teicoplanin A3-1, a fused ring structure to which two carbohydrates (mannose and N-acetylglucosamine) are attached. The major and minor components also contain a third carbohydrate moiety, β-D-glucosamine, and differ only by the length and conformation of a side chain attached to it. It′s mechanism of action is through inhibition of bacterial cell wall biosynthesis. |
| Other Notes: | Keep container tightly closed in a dry and well-ventilated place. |
| Other Notes: | Mixture of six primary teicoplanins; primarily teicoplanins A2 group. |
| Packaging: | 100MG,1G |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥80% (teicoplanins A2, HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 51101500 |