Sodium thioglycolate

SIGMA/T0632 - ≥96.5% (iodometric)

Synonym: Mercaptoacetic acid sodium salt; Thioglycolic acid sodium salt

CAS Number: 367-51-1
Empirical Formula (Hill Notation): C₂H₃NaO₂S
Molecular Weight: 114.10
EC Number: 206-696-4
MDL Number: MFCD00043386
Linear Formula: HSCH₂COONa
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-T0632-25G	25 g	$54.30 1/EA	Add To Favorites
45-T0632-100G	100 g	$90.20 1/EA	Add To Favorites
45-T0632-500G	500 g	$345.00 1/EA	Add To Favorites

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This image depicts SKU: T0632-25G

Properties
Descriptions
Safety Info.
Basic Data

assay	≥96.5% (iodometric)
form	powder
InChI	1S/C2H4O2S.Na/c3-2(4)1-5;/h5H,1H2,(H,3,4);/q;+1/p-1
InChI key	GNBVPFITFYNRCN-UHFFFAOYSA-M
mp	>300 °C (lit.)
Quality Level	200
SMILES string	[Na+].[O-]C(=O)CS
storage temp.	−20°C

Application:	Sodium thioglycolate has been used: • as a growth supplement in enrichment media and to study its effect on Arcobacter • in influenza hemagglutinin formulation in order to reduce disulfide-mediated cross-linking and early potency loss • in electron microscopy
Biochem/physiol Actions:	Sodium thioglycolate acts as reducing agent and is suitable for anaerobic and microaerophilic bacterial growth.
Biochem/physiol Actions:	Sodium thioglycolate is a commonly used reagent for bacteriological research to maintain reducing conditions in media. Thioglycolate can also protect enzymes against inactivation by maintaining protein thiol groups in the reduced state. Thioglycolate medium is frequently used in inflammation research to elicit a neutrophil and macrophage response in vivo.
Caution:	At room temperature, concentrations over 70% in water tend to form 1-2% thioglycolides per month which hydrolyze to the original free compound when made acidic or alkaline. The 70% solution oxidizes in air but is stable at room temperature when tightly closed. Thioglycolate salts may also lose purity on storage. The exclusion of air does not materially improve stability.
Packaging:	25, 100, 500 g in poly bottle

Symbol	GHS05,GHS06
Signal word	Danger
Hazard statements	H290 - H301 - H312 - H317
Precautionary statements	P234 - P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312
Hazard Codes	Xn
Risk Statements	22-38
Safety Statements	36
RIDADR	UN 3335
WGK Germany	WGK 1

Purity	≥96.5% (iodometric)
mp	>300 °C (lit.)
Storage Temp.	−20°C
UNSPSC	12352201

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