Sodium thioglycolate
SIGMA/T0632 - ≥96.5% (iodometric)
Synonym: Mercaptoacetic acid sodium salt; Thioglycolic acid sodium salt
CAS Number: 367-51-1
Empirical Formula (Hill Notation): C2H3NaO2S
Molecular Weight: 114.10
EC Number: 206-696-4
MDL Number: MFCD00043386
Linear Formula: HSCH2COONa
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: T0632-25G
This image depicts SKU: T0632-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: T0632-100G
This image depicts SKU: T0632-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: T0632-500G
This image depicts SKU: T0632-500G
| assay | ≥96.5% (iodometric) |
| color | white to off-white |
| form | powder |
| InChI | 1S/C2H4O2S.Na/c3-2(4)1-5; |
| InChI key | GNBVPFITFYNRCN-UHFFFAOYSA |
| mp | >300 °C (lit.) |
| Quality Level | 200  |
| SMILES string | [Na+].[O-]C(=O)CS |
| solubility | water: ~609.1 g/L at 20 °C (OECD Test Guideline 105) |
| storage temp. | −20°C |
| useful pH range | 6.7 (20 °C, 100 g/L) |
| Application: | Sodium thioglycolate has been used: • as a growth supplement in enrichment media and to study its effect on Arcobacter • in influenza hemagglutinin formulation in order to reduce disulfide-mediated cross-linking and early potency loss • in electron microscopy |
| Biochem/physiol Actions: | Sodium thioglycolate acts as reducing agent and is suitable for anaerobic and microaerophilic bacterial growth. |
| Biochem/physiol Actions: | Sodium thioglycolate is a commonly used reagent for bacteriological research to maintain reducing conditions in media. Thioglycolate can also protect enzymes against inactivation by maintaining protein thiol groups in the reduced state. Thioglycolate medium is frequently used in inflammation research to elicit a neutrophil and macrophage response in vivo. |
| Disclaimer: | At room temperature, concentrations over 70% in water tend to form 1-2% thioglycolides per month which hydrolyze to the original free compound when made acidic or alkaline. The 70% solution oxidizes in air but is stable at room temperature when tightly closed. Thioglycolate salts may also lose purity on storage. The exclusion of air does not materially improve stability. |
| Other Notes: | To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page. |
| Packaging: | 25, 100, 500 g in poly bottle |
| Symbol |   GHS05,GHS06 |
| Signal word | Danger |
| Hazard statements | H290 - H301 - H312 - H317 |
| Precautionary statements | P234 - P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 |
| Hazard Codes | Xn |
| Risk Statements | 22-38 |
| Safety Statements | 36 |
| RIDADR | UN 3335 |
| WGK Germany | WGK 1 |
| Purity | ≥96.5% (iodometric) |
| mp | >300 °C (lit.) |
| Storage Temp. | −20°C |
| UNSPSC | 12352201 |