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Tropisetron monohydrochloride

SIGMA/T104 - solid, ≥98% (HPLC)

Synonym: 1H-Indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester monohydrochloride; 3-Tropanylindole-3-carboxylate monohydrochloride; ICS-205,930; Navoban

CAS Number: 105826-92-4
Empirical Formula (Hill Notation): C17H20N2O2 · HCl
Molecular Weight: 320.81
MDL Number: MFCD00210221
Linear Formula: C17H20N2O2 · HCl
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-T104-50MG 50 mg
$862.00
1/EA
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assay ≥98% (HPLC)
form solid
InChI 1S/C17H20N2O2.ClH/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16;/h2-5,10-13,18H,6-9H2,1H3;1H
InChI key XIEGSJAEZIGKSA-UHFFFAOYSA-N
originator Novartis
Quality Level 100 
SMILES string Cl[H].CN1C2CCC1CC(C2)OC(=O)c3c[nH]c4ccccc34
solubility H2O: >10 mg/mL
storage temp. 2-8°C
Application: Tropisetron monohydrochloride was used as a standard to determine the tropisetron in human plasma using HPLC method with UV detection.
Biochem/physiol Actions: 3-Tropanylindole-3-carboxylate hydrochloride is a selective 5-HT3 serotonin receptor antagonist.
Biochem/physiol Actions: Tropisetron a selective serotonin 5-HT3 receptor antagonist is used mainly as an antiemetic to treat nausea and vomiting following chemotherapy . In the treatment of fibromyalgia syndrome (FMS) tropisetron reduced not only pain perception but also had a favourable effect on cardiac dysfunction during treatment.
Features and Benefits: This compound is featured on the Acetylcholine Receptors (Nicotinic)  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits: This compound was developed by Novartis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 50 mg in poly bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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