DMT-dT Phosphoramidite
SIGMA/T111040 - configured for MerMade
Synonym: 5′-O-(4,4′-dimethoxytrityl)-2′-deoxythymidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]; 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxythymidine, 3′-[2-cyanoethyl N,N-
CAS Number: 98796-51-1
Empirical Formula (Hill Notation): C40H49N4O8P
Molecular Weight: 744.81
MDL Number: MFCD00055063
Linear Formula: C40H49N4O8P
Product Type: Chemical
λ | conforms (UV/VIS Identity) |
assay | ≥99% (31P-NMR) |
≥99.0% (reversed phase HPLC) | |
biological source | non-animal source (no BSE/TSE risk) |
color | white to off-white |
compatibility | configured for MerMade |
form | powder or granules |
impurities | ≤0.3 wt. % water content (Karl Fischer) |
InChI | 1S/C40H49N4O8P/c1-27(2)44 |
InChI key | UNOTXUFIWPRZJX-CEXSRUIHSA |
nucleoside profile | base: deoxythymidine base protecting group: none 2' protecting group: none 5' protecting group: DMT deprotection: fast/standard |
product line | Proligo Reagents |
Quality Level | 200 |
SMILES string | COc1ccc(cc1)C(OC[C@H]2O[C |
storage temp. | 2-8°C |
technique(s) | oligo synthesis: suitable |
type | for DNA synthesis |
General description: | DMT-dT Phosphoramidite belongs to the class of DNA Phosphoramidites.The key features of standard protected DNA phosphoramidite are:• Exocyclic amine functions are protected by a benzoyl group (dA(bz) and dC(bz)) or isobutyryl group (dG(ib)) • Recommended cleavage and deprotection conditions are 8 hours at 55 °C or 24 hours at room temperature using concentrated ammonia solution for standard base-protected oligonucleotides • The high coupling efficiency of Proligo′s DNA phosphoramidites leads to high-yield and high-quality oligonucleotides (a) |
Packaging: | T111040-1G packaged in a 1 oz bottle with a 28-400 cap T111040-10G packaged in a 8 oz bottle with a 28-400 cap T111040-6x5G packaged in a 8 oz bottle with a 28-400 cap T111040-6x10G packaged in a 8 oz bottle with a 28-400 cap T111040-20x10G packaged in a 1 L bottle with GL 45 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥99% (31P-NMR); ≥99.0% (reversed phase HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |