Thyroglobulin from porcine thyroid gland
SIGMA/T1126 - powder
Synonym: TG human
CAS Number: 9010-34-8
EC Number: 232-721-3
MDL Number: MFCD00132429
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T1126-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T1126-500MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T1126-1G
| ash | ≤4% |
| biological source | Porcine thyroid |
| composition | Iodine, ≥0.3% |
| form | powder |
| mol wt | ~670 kDa |
| nitrogen analysis | 14.0-17.5% total |
| pI | 4.58 |
| Quality Level | 200  |
| storage temp. | −20°C |
| technique(s) | protein purification: suitable |
| UniProt accession no. | F1RRV3  |
| Biochem/physiol Actions: | Thyroglobulin has been shown to regulate the transcription of iodide porters including sodium iodide symporter and pendrin. |
| Biochem/physiol Actions: | Thyroglobulin is a major protein involved with iodine metabolism. It consists of an iodine-containing protein that is stored in the thyroid gland and is converted into circulating thyroxines when the thyroid is stimulated by TSH (Thyroid Stimulating Hormone) from the pituitary. Thyroglobulin is often used as a carrier protein for the production of antibodies. Its advantage as a carrier protein comes from its large number of tyrosine residues that can be used for conjugation using the diazo reaction. |
| Other Notes: | Electrophoretically heterogeneous. |
| Packaging: | 1 g in poly bottle |
| Packaging: | 100, 500 mg in poly bottle |
| Preparation Note: | When reconstituted in water (20 mg/ml), a turbid solution with some insolubles is observed. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |