(+)-α-Tocopherol acetate
SIGMA/T1157 - BioReagent, suitable for insect cell culture, ~1360 IU/g
Synonym: Vitamin E acetate
CAS Number: 58-95-7
Empirical Formula (Hill Notation): C31H52O3
Molecular Weight: 472.74
EC Number: 200-405-4
MDL Number: MFCD00072052
Linear Formula: C31H52O3
Product Type: Chemical
| biological source | plant |
| color | white to yellow |
| description | Synthesized from natural α-tocopherol |
| form | liquid (or semi-solid) |
| InChI | 1S/C31H52O3/c1-21(2)13-10 |
| InChI key | ZAKOWWREFLAJOT-CEFNRUSXSA |
| mol wt | Mw 472.74 g/mol |
| product line | BioReagent |
| purified by | crystallization |
| Quality Level | 200  |
| SMILES string | CC(C)CCC[C@@H](C)CCC[C@@H |
| solubility | chloroform: soluble 50 mg/mL, clear, colorless to yellow |
| specific activity | ~1360 IU/g |
| storage temp. | room temp |
| technique(s) | cell culture | insect: suitable |
| Application: | (+)-α-Tocopherol acetate has been used: • as a supplement in the human embryonic kidney cells (HEK 293) to assess its impact on cell growth • as a component of Dulbecco′s Modified Eagle Medium/Nutrient Mixture F-12 (DMEM/F12) for immortalized chondrocyte cell line • as a component of serum-free medium for human colon tissue organ culture • to test its antioxidant effects on cow articular chondrocytes |
| Application: | Use in insect cell culture applications as an antioxidant. |
| Biochem/physiol Actions: | α-Tocopherol acetate or vitamin E-acetate has antioxidant properties and reduces lipid peroxidation. However, vitamin E acetate on pyrolysis leads to the generation of carcinogens like alkenes and benzenes. |
| Caution: | Since the M.P. is about 25 °C this preparation is usually an oil. Does not air oxidize. |
| General description: | α-Tocopherol acetate is a semisynthetic acetate ester of naturally occurring α-tocopherol. |
| Packaging: | 1, 10 g in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | 230.0 °F - closed cup |
| Flash Point(C) | 110 °C - closed cup |
| activity | specific activity: ~1360 IU/g |
| Storage Temp. | room temp |
| UNSPSC | 12352200 |