Thioperamide maleate salt
SIGMA/T123 - solid
Synonym: MR-12842; N-
CAS Number: 148440-81-7
Empirical Formula (Hill Notation): C15H24N4S · C4H4O4
Molecular Weight: 408.52
MDL Number: MFCD00083209
Linear Formula: C15H24N4S · C4H4O4
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white |
form | solid |
InChI | 1S/C16H25N3S.C4H4O4/c20-1 |
InChI key | REZRBLGMJZZSID-BTJKTKAUSA |
SMILES string | OC(=O)C=C/C(O)=O.S=C(CC1 |
solubility | DMSO: 12 mg/mL |
ethanol: 3 mg/mL | |
H2O: >10 mg/mL | |
storage condition | desiccated |
under inert gas |
Application: | Thioperamide maleate salt was used to study the sympathetic and autonomic nerve activity in mammalian white adipose tissue. |
Biochem/physiol Actions: | Potent and selective H3 histamine receptor antagonist that crosses the blood-brain barrier. |
Biochem/physiol Actions: | Thioperamide is a potent and selective H3 histamine receptor antagonist that crosses the blood-brain barrier. It affects the central histaminergic system and decreases the duration of seizures and convulsions in mice. It also improves learning deficit induced by other drugs such as scopolamine. |
Features and Benefits: | This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
Packaging: | 10, 25, 100 mg in poly bottle |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
UNSPSC | 12352200 |