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Thioperamide maleate salt

SIGMA/T123 - solid

Synonym: MR-12842; N-Cyclohexyl-4-(1H-imidazol-4-yl)-1-piperidinecarbothioamide maleate salt

CAS Number: 148440-81-7
Empirical Formula (Hill Notation): C15H24N4S · C4H4O4
Molecular Weight: 408.52
MDL Number: MFCD00083209
Linear Formula: C15H24N4S · C4H4O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-T123-10MG 10 mg
 $144.00
1/EA		 Add To Favorites
45-T123-25MG 25 mg
 $345.00
1/EA		 Add To Favorites
45-T123-100MG 100 mg
 $1040.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T123-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T123-10MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T123-25MG

 

assay ≥98% (HPLC)
color white
form solid
InChI 1S/C16H25N3S.C4H4O4/c20-16(10-13-4-2-1-3-5-13)19-8-6-14(7-9-19)15-11-17-12-18-15;5-3(6)1-2-4(7)8/h11-14H,1-10H2,(H,17,18);1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key REZRBLGMJZZSID-BTJKTKAUSA-N
Quality Level 200 
SMILES string OC(=O)C=C/C(O)=O.S=C(CC1CCCCC1)N2CCC(CC2)c3c[nH]cn3
solubility DMSO: 12 mg/mL
  ethanol: 3 mg/mL
  H2O: >10 mg/mL
storage condition desiccated
  under inert gas
Application: Thioperamide maleate salt was used to study the sympathetic and autonomic nerve activity in mammalian white adipose tissue.
Biochem/physiol Actions: Potent and selective H3 histamine receptor antagonist that crosses the blood-brain barrier.
Biochem/physiol Actions: Thioperamide is a potent and selective H3 histamine receptor antagonist that crosses the blood-brain barrier. It affects the central histaminergic system and decreases the duration of seizures and convulsions in mice. It also improves learning deficit induced by other drugs such as scopolamine.
Features and Benefits: This compound is featured on the Histamine Receptors  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 10, 25, 100 mg in poly bottle
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
UNSPSC 12352200

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