apo-Transferrin bovine
SIGMA/T1428 - BioReagent, suitable for cell culture, ≥98%
Synonym: Human serotransferrin
CAS Number: 11096-37-0
EC Number: 234-318-8
MDL Number: MFCD00130536
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T1428-10G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T1428-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T1428-500MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T1428-50MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T1428-5G
| assay | ≥98% |
| biological source | bovine |
| form | powder |
| impurities | iron, essentially free |
| product line | BioReagent |
| Quality Level | 200  |
| solubility | H2O: 10 mg/mL |
| storage temp. | 2-8°C |
| technique(s) | cell culture | mammalian: suitable |
| UniProt accession no. | Q29443  |
| Application: | All cells require iron for the proper uptake of oxygen from their environment. Transferrin, a protein isolated from serum, causes the uptake and transport of iron from culture medium to the cells. This allows proper oxygen uptake and also stimulates growth-related enzyme activity. Iron-saturated transferrin (holo transferrin) is continually recycled after releasing iron and becomes iron-deficient transferrin (apo-transferrin). Choosing which form to use depends upon the culture conditions. In media such as Dulbecco′s Modified Eagle′s Medium/Ham′s Nutrient Mixture F12 (DMEM/F12) that contain high levels of iron salt, using apo-transferrin is preferred. |
| Application: | apo-Transferrin bovine has been used as a component of: • basal medium for culturing bovine mammary epithelial cells • minimum essential medium α (MEM-α) for spermatogonial stem cells (SSCs) culture • induction medium for mesenchymal stem cell culture |
| Biochem/physiol Actions: | apo-Transferrin (apoTf) aids in preventing iron accumulation in tissues, especially in non-transfusion dependent β-thalassemia. |
| General description: | apo-Transferrin is an iron-free form of transferrin that is present in circulation. |
| Packaging: | 5, 10 g in poly bottle |
| Packaging: | 50, 100, 500 mg in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352204 |