Synonym: 1,4-Bis-[2-(3,5-dichloropyridyloxy)]benzene; 3,3′,5,5′-Tetrachloro-1,4-bis(pyridyloxy)benzene
CAS Number: 76150-91-9
Empirical Formula (Hill Notation): C16H8N2O2Cl4
Molecular Weight: 402.06
MDL Number: MFCD00057368
Linear Formula: C16H8N2O2Cl4
Product Type: Chemical
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts T1443-5MG.
| assay |
≥98% (HPLC) |
| color |
white |
| form |
solid |
| InChI |
1S/C16H8Cl4N2O2/c17-9-5-13(19)15(21-7-9)23-11-1-2-12(4-3-11)24-16-14(20)6-10(18)8-22-16/h1-8H |
| InChI key |
BAFKRPOFIYPKBQ-UHFFFAOYSA-N |
| Quality Level |
100  |
| SMILES string |
Clc1cnc(Oc2ccc(Oc3ncc(Cl)cc3Cl)cc2)c(Cl)c1 |
| solubility |
DMSO: >10 mg/mL |
| |
H2O: insoluble |
| storage temp. |
2-8°C |
| Application: |
TCPOBOP has been used for enhancing Mcl-1-Italics promoter functions in mouse hepatoma cells. TCPOBOP has also been used to study constitutive androstane receptor(CAR)-induced gene expression in mouse hepatocytes. |
| Biochem/physiol Actions: |
TCPOBOP enhances the nuclear receptor CAR transactivation of cytochrome P450 (CYP), as dose-dependent direct agonist of CAR. |
| Biochem/physiol Actions: |
TCPOBOP enhances the nuclear receptor CAR transactivation of cytochrome P450 (CYP), as dose-dependent direct agonist of CAR. The most potent known member of the phenobarbital-like class of CYP-inducing agents. |
| Features and Benefits: |
This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
| Packaging: |
5 mg in glass bottle |
| Preparation Note: |
TCPOBOP is soluble in DMSO at a concentration that is greater than 10 mg/ml. It is insoluble in water. |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352200 |