Anti-Tumor Necrosis Factor-α antibody produced in goat
SIGMA/T1816 - affinity isolated antibody, lyophilized powder
Synonym: Anti-TNF-α
Product Type: Chemical
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| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | goat |
| clone | polyclonal |
| conjugate | unconjugated |
| form | lyophilized powder |
| Quality Level | 200  |
| species reactivity | pig |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: 15 μg/mL |
| indirect ELISA: 0.5-1.0 μg/mL | |
| neutralization: suitable | |
| western blot: 0.1-0.2 μg/mL | |
| UniProt accession no. | P23563  |
| Application: | Anti-Tumor Necrosis Factor-α antibody can be used in immunohistochemistry and indirect ELISA. |
| Biochem/physiol Actions: | The antibody neutralizes the biological activity of recombinant porcine TNF-α. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Tumor Necrosis Factor-α (TNF-α) also refers as cachectin is a cytokine produced in response to immunological challenges such as bacteria (lipopolysaccharides), parasites, mitogens, viruses and other cytokines. It has essential roles in antitumor activity, inflammation, septic shock, immune modulation, anorexia, cachexia, hematopoiesis and viral replication. It also facilitates the growth of human fibroblasts, collagenase production as well as can activates polymorphonuclear neutrophils and osteoclasts. Anti-Tumor Necrosis Factor-α antibody can be used in neutralization and immunoblotting (working concentration-0.1-0.2 μg/ml) for detecting porcine TNF-α. Goat anti-Tumor Necrosis Factor-α antibody reacts specifically with recombinant porcine tumor necrosis factor α. |
| Immunogen: | recombinant porcine TNF-α expressed in Escherichia coli. |
| Physical form: | Lyophilized from a 0.2 μm filtered solution of phosphate buffered saline. |
| Storage Temp. | −20°C |
| UNSPSC | 51111800 |