Anti-TrkB antibody produced in goat
SIGMA/T1941 - affinity isolated antibody, lyophilized powder
Synonym: Anti-DEE58; Anti-EIEE58; Anti-GP145-TrkB; Anti-OBHD; Anti-TRKB; Anti-trk-B
MDL Number: MFCD01092509
Product Type: Chemical
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| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | goat |
| clone | polyclonal |
| conjugate | unconjugated |
| form | lyophilized powder |
| Quality Level | 200  |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | flow cytometry: 2.5 μg/mL (per 106 cells) |
| western blot: 0.25-0.5 μg/mL | |
| UniProt accession no. | Q16620  |
| Biochem/physiol Actions: | The development and maintenance of central and peripheral nervous system is controlled by a family of Trk family of neurotrophin receptors. The Trk family consists of 3 members, TrkA (NTRK1), Trk B (NTRK2) and TrkC (NTRK3). Neurotrophins have an important role in development of the nervous system and mediate the cellular effects by binding to the Trk receptors. Trk receptors reportedly play a major role in the development and behaviour of neuroblastomas and other type of cancers. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | The antibody recognizes recombinant human TrkB. It shows no cross-reactivity with TrkC, NT-3, NT-4, BDNF and NGF-β. |
| Immunogen: | recombinant human TrkB extracellular domain expressed in NS0 cells. |
| Physical form: | Lyophilized from a 0.2 μm filtered solution of phosphate buffered saline containing 5% trehalose. |
| Hazard statements | H412 |
| Precautionary statements | P273 - P501 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 51111800 |