Trequinsin hydrochloride
SIGMA/T2057 - ≥98%
Synonym: HL 725
CAS Number: 78416-81-6
Empirical Formula (Hill Notation): C24H27N3O3 · HCl
Molecular Weight: 441.95
MDL Number: MFCD01076563
Linear Formula: C24H27N3O3 · HCl
Product Type: Chemical
assay | ≥98% |
form | powder |
InChI | 1S/C24H27N3O3.ClH/c1-14-9 |
InChI key | DTCZZBVPTHVXFA-OSMRDGEFSA |
Quality Level | 100 ![]() |
SMILES string | Cl[H].COc1cc2CCN3C(=O)N(C |
Application: | Trequinsin has been used as a PDE3 inhibitor in rat juxtaglomerular cells. This study reported that trequinsin can enhance cellular cAMP content, forskolin-induced cAMP synthesis, and renin release in cells. |
Biochem/physiol Actions: | Phosphodiesterase III inhibitor. |
Biochem/physiol Actions: | Trequinsin is a strong antihypertensive agent that has a hemodynamic profile similar to that of arteriolar dilators. Trequinsin can block platelet aggregation and also inhibit tissue factor expression in human endothelial cells,. |
Features and Benefits: | This compound is a featured product for Cyclic Nucleotide research. Click here ![]() ![]() |
Features and Benefits: | This compound is featured on the Phosphodiesterases ![]() ![]() |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% |
UNSPSC | 41106305 |