Synonym: N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide
CAS Number: 293754-55-9
Empirical Formula (Hill Notation): C17H12NSO3F9
Molecular Weight: 481.33
MDL Number: MFCD03412028
Linear Formula: C17H12NSO3F9
Product Type: Chemical
| assay |
≥98% |
| InChI |
1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 |
| InChI key |
SGIWFELWJPNFDH-UHFFFAOYSA-N |
| mol wt |
481.3 |
| Quality Level |
200  |
| SMILES string |
OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c2ccccc2)(C(F)(F)F)C(F)(F)F |
| storage temp. |
−20°C |
| Application: |
T0901317 has been used in LXR agonist study in order to observe the expression of all dietary cholesterol-regulated genes in mice. It has also been used to stimulate the radiolabeled peritoneal macrophages from WT (wildtype) and Tg (transgenic) mice for cellular cholesterol efflux assay. |
| Biochem/physiol Actions: |
LXR agonist whose treatment results in an LXR-dependent up-regulation of ABC1 gene expression |
| Biochem/physiol Actions: |
T0901317 can prevent the secretion of insulin by acting on the metabolism of mitochondria. |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% |
| Storage Temp. |
−20°C |
| UNSPSC |
12352106 |
