Synonym: 3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine sodium salt; Sodium levothyroxine; T4
CAS Number: 6106-07-6
Empirical Formula (Hill Notation): C15H10I4NNaO4 · 5H2O
Molecular Weight: 888.93
EC Number: 200-221-4
MDL Number: MFCD00149110
Linear Formula: HOC6H2I2OC6H2I2CH2CH(NH2)COONa · 5H2O
Product Type: Chemical
assay |
≥98% (HPLC) |
biological source |
synthetic (organic) |
form |
powder |
InChI |
1S/C15H11I4NO4.Na.5H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;;;;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;5*1H2/q;+1;;;;;/p-1/t12-;;;;;;/m0....../s1 |
InChI key |
JMHCCAYJTTWMCX-QWPJCUCISA-M |
mp |
207-210 (dec.) (lit.) |
Quality Level |
200 |
shipped in |
ambient |
SMILES string |
O.O.O.O.O.[Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O |
solubility |
4 M NH4OH in methanol: 50 mg/mL, clear to hazy, colorless to yellow |
sterility |
non-sterile |
storage temp. |
−20°C |
Biochem/physiol Actions: |
L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis. |
Packaging: |
1, 5 g in glass bottle |
Preparation Note: |
L-Thyroxine sodium salt pentahydrate dissolves in 4 N NH4OH in methanol at 50 mg/ml to yield a clear to hazy, colorless to yellow solution. |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥98% (HPLC) |
mp |
207-210 (dec.) (lit.) |
Storage Temp. |
−20°C |
UNSPSC |
51111800 |