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3,3′,5-Triiodo-L-thyronine sodium salt

SIGMA/T2752 - ≥95% (HPLC)

Synonym: Liothyronine; O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine sodium salt; T3

CAS Number: 55-06-1
Empirical Formula (Hill Notation): C15H11I3NNaO4
Molecular Weight: 672.96
EC Number: 200-223-5
MDL Number: MFCD00002594
Linear Formula: C15H11I3NNaO4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-T2752-1G 1 g
 $292.00
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assay ≥95% (HPLC)
biological source synthetic (organic)
form powder
InChI 1S/C15H12I3NO4.Na/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22;/h1-4,6,12,20H,5,19H2,(H,21,22);/q;+1/p-1/t12-;/m0./s1
InChI key SBXXSUDPJJJJLC-YDALLXLXSA-M
Quality Level 200 
shipped in ambient
SMILES string [Na+].N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C([O-])=O
solubility ethanol/1 M HCl (4:1): 10 mg/mL, clear, colorless to faintly yellow or pink
storage temp. −20°C
technique(s) cell culture | mammalian: suitable
Application: 3,3′,5-Triiodo-L-thyronine sodium salt was used in Oligodendrocyte differentiation medium used for isolation and culture of rat and mouse oligodendrocyte precursor cells. The product was used as a test compound for incubating adipocyte cells, used for studying the impact of hormones and butyrate on modulation of porcine adipocyte beta-adrenergic receptors.
Biochem/physiol Actions: 3,3′,5-Triiodo-L-thyronine also referred to as O-(4-Hydroxy-3-iodophenyl)−3,5−diiodo-L-tyrosine sodium salt or T3 is the biologically active thyroid hormone. In hypothyroidism pateints, triiodothyronine can enhance mood and neuropsychological function. The product also positively regulates the hepatic FGF21 expression and stimulates the metabolic breakdown of glucose, fats, and proteins by enhancing the levels of numerous metabolic enzymes such as hexokinase, liver glucose 6-phosphatase as well as mitochondrial enzymes for oxidative phosphorylation.
Packaging: 1 g in poly bottle
Packaging: 100, 250, 500 mg in poly bottle
Preparation Note: 3,3′,5-Triiodo-L-thyronine sodium salt dissolves in 1 M HCl:EtOH with a ratio of 1:4 at 10 mg/ml to yield a clear, colorless to yellow or faint pink solution.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95% (HPLC)
Storage Temp. −20°C
UNSPSC 51111800

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