3,3′,5-Triiodo-L-thyronine

SIGMA/T2877 - ≥95% (HPLC), powder

Synonym: O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine; Liothyronine; T₃

CAS Number: 6893-02-3
Empirical Formula (Hill Notation): C₁₅H₁₂I₃NO₄
Molecular Weight: 650.97
EC Number: 229-999-3
MDL Number: MFCD00002593
Linear Formula: C₁₅H₁₂I₃NO₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-T2877-100MG	100 mg	$72.20 1/EA	Add To Favorites
45-T2877-250MG	250 mg	$149.00 1/EA	Add To Favorites
45-T2877-500MG	500 mg	$254.00 1/EA	Add To Favorites
45-T2877-1G	1 g	$397.00 1/EA	Add To Favorites
45-T2877-5G	5 g	$1530.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T2877-1G

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95% (HPLC)
biological source	synthetic (organic)
form	powder
InChI	1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1
InChI key	AUYYCJSJGJYCDS-LBPRGKRZSA-N
mp	234-238 °C (lit.)
optical activity	[α]25/D +23.0°, c = 2 in 1 N HCl: ethanol, 1:2
Quality Level	200
shipped in	ambient
SMILES string	N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O
solubility	4 M NH₄OH in methanol: 5 mg/mL, clear to very slightly hazy, colorless to light yellow
sterility	non-sterile
storage temp.	−20°C
technique(s)	transfection: suitable

Application:	3,3′,5-Triiodo-L-thyronine can be used for Insulin-like growth factor I assays performed by using a double antibody radioimmunoassay. The product can also be used for in vitro transfection of 293T cells.
Biochem/physiol Actions:	3,3′,5-Triiodo-L-thyronine also referred to as O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine or T3 is the biologically active thyroid hormone. In hypothyroidism pateints, triiodothyronine enhances mood and neuropsychological function. The product also positively regulates the hepatic FGF21 expression and stimulates the metabolic breakdown of glucose, fats, and proteins by enhancing the levels of numerous metabolic enzymes such as hexokinase, liver glucose 6-phosphatase as well as mitochondrial enzymes for oxidative phosphorylation. Additionally, the product facilitates the normal body growth in children and is pivotal for central nervous system maturation in foetus.
Packaging:	1, 5 g in poly bottle
Packaging:	100, 250, 500 mg in poly bottle
Preparation Note:	3,3′,5-Triiodo-L-thyronine dissolves in 4M NH4OH in MeOH at 5 mg/ml to yield a colorless to light yellow, clear to very slightly hazy solution.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95% (HPLC)
mp	234-238 °C (lit.)
Storage Temp.	−20°C
UNSPSC	51111800

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