Advanced Search



Tomatidine hydrochloride

SIGMA/T2909 - ≥85%

Synonym: 3β-Hydroxy-5α-tomatidane hydrochloride; 5α-Tomatidan-3β-ol hydrochloride

CAS Number: 6192-62-7
Empirical Formula (Hill Notation): C27H45NO2 · HCl
Molecular Weight: 452.11
MDL Number: MFCD00133866
Linear Formula: C27H45NO2 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-T2909-25MG 25 mg
 $86.00
1/EA		 Add To Favorites
45-T2909-100MG 100 mg
 $296.00
1/EA		 Add To Favorites
assay ≥85%
InChI 1S/C27H45NO2.ClH/c1-16-7-12-27(28-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(29)8-10-25(18,3)21(20)9-11-26(22,24)4;/h16-24,28-29H,5-15H2,1-4H3;1H/t16-,17-,18-,19-,20+,21-,22-,23-,24-,25-,26-,27+;/m0./s1
InChI key SXXHVPYRDFJKPG-XRWUXUKGSA-N
Quality Level 100 
SMILES string Cl[H].[H][C@@]12CC[C@]3([H])[C@]([H])(CC[C@@]4(C)[C@@]3([H])C[C@]5([H])O[C@]6(CC[C@H](C)CN6)[C@@H](C)[C@]45[H])[C@@]1(C)CC[C@H](O)C2
storage temp. 2-8°C
Application: Tomatidine hydrochloride has been used:
• to evaluate its effect on nasopharyngeal carcinoma using cell proliferation and flow cytometry assay
• as a negative control in the non-specific inhibition on hedgehog signaling in hepatocellular carcinoma cell lines
• as a control for cell growth assay and expression studies in pancreatic cancer cells
Biochem/physiol Actions: Potent inhibitor of Staphylococcus aureus small-colony variants typically seen as complications of cystic fibrosis, with little or no effect on normal S. aureus strains. Also shows antiinflammatory activity by indirectly inhibiting iNOS and COX-2 pathways.
Biochem/physiol Actions: Tomatidine induces the anti-oxidant nuclear factor E2-related factor 2 (Nrf2) and mitophagy, favoring the delay in aging process in C.elegans. It is an inhibitor of muscle atrophy and promotes anabolism in muscle by activating mammalian target of rapamycin complex 1 (mTORC1). It may be useful for treating skeletal muscle atrophy.
General description: Tomatidine is a glycoalkaloid and an aglycone metabolite of tomatine present in high levels in unripe tomato.
Packaging: 25, 100 mg in poly bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Precautionary statements P264 - P270 - P301 + P312 - P501
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥85%
Storage Temp. 2-8°C
UNSPSC 41116107

The following items have been added to your cart:

Choose a favorite list for this item:
Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Year Price Updates

We are currently working diligently to update our website pricing information for the New Year. If you place an order, you will be acknowledged with any corrected pricing. If you'd like the most current information sooner, please don't hesitate to drop us an email or give us a call and we'd be happy to assist. Thank you for your patience while we are updating.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top