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Tetrabenazine

SIGMA/T2952 - ≥98% (HPLC), solid

Synonym: 9,10-Dimethoxy-1,3,4,6,7,11b-hexahydro-3-isobutyl-(rel 3R,11bR)-2H-benzo[a]quinolizin-2-one

CAS Number: 58-46-8
Empirical Formula (Hill Notation): C19H27NO3
Molecular Weight: 317.42
EC Number: 200-383-6
MDL Number: MFCD08461052
Linear Formula: C19H27NO3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-T2952-10MG 10 mg
 $179.00
1/EA		 Add To Favorites
45-T2952-50MG 50 mg
 $825.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts T2952-50MG.

 

assay ≥98% (HPLC)
form solid
InChI 1S/C19H27NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16H,5-7,10-11H2,1-4H3/t14-,16-/m1/s1
InChI key MKJIEFSOBYUXJB-GDBMZVCRSA-N
originator Roche
Quality Level 100 
SMILES string COc1cc2CCN3C[C@@H](CC(C)C)C(=O)CC3c2cc1OC
solubility DMSO: >10 mg/mL
  H2O: insoluble
storage temp. 2-8°C
Application: Tetrabenazine has been used for dopamine uptake assays in mouse brain cells1. Tetrabenazine has also been used for non-specific binding assays in postnuclear supernatants derived from PC-12 and CV-1 cells2.
Biochem/physiol Actions: Tetrabenazine is a reversible type 2 vesicular monoamine transporter (VMAT) inhibitor.
Biochem/physiol Actions: Tetrabenazine is a reversible type 2 vesicular monoamine transporter (VMAT) inhibitor. It depletes dopamine stores.
Features and Benefits: This compound was developed by Roche . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 10, 50 mg in glass bottle
Preparation Note: Tetrabenazine is soluble in DMSO at a concentration that is greater than 10 mg/ml and is insoluble in water.
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Precautionary statements P264 - P270 - P301 + P312 - P501
Hazard Codes Xn
Risk Statements 22
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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