Thrombin generation chromogenic substrate
SIGMA/T3068 - ≥90% (HPLC), solid
Synonym: β-Ala-Gly-Arg-p-nitroanilide diacetate
Empirical Formula (Hill Notation): C21H34N8O9
Molecular Weight: 542.54
MDL Number: MFCD03453625
Linear Formula: C21H34N8O9
Product Type: Chemical
| assay | ≥90% (HPLC) |
| biological source | synthetic (organic) |
| form | solid |
| InChI key | PBMJNSQKWBTVOL-GXKRWWSZSA |
| Quality Level | 200 ![]() |
| SMILES string | [N+](=O)([O-])c1ccc(cc1)N |
| storage temp. | 2-8°C |
| technique(s) | activity assay: suitable |
| Amino Acid Sequence: | Ala-Gly-Arg-pNA |
| Application: | Thrombin generation chromogenic substrate can be used for chromogenic assay developed through aptamer affinity capture and a subsequent enzyme reaction for detecting the thrombin in dilute human serum. |
| Biochem/physiol Actions: | Thrombin generation chromogenic substrate also known as beta-Ala-Gly-Arg para-nitroanilide, is proteolytically cleaved by human thrombin and produces beta-Ala-Gly-Arg and p-nitroanilide. The release of p-nitroanilide is quatified for assesing the anti-thrombin activity. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥90% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352204 |

