Tetracycline

SIGMA/T3258 - 98.0-102.0% (HPLC)

Synonym: Tetracycline Hydrate

CAS Number: 60-54-8
Empirical Formula (Hill Notation): C₂₂H₂₄N₂O₈ · xH₂O
Molecular Weight: 444.43 (anhydrous basis)
EC Number: 200-481-9
MDL Number: MFCD00151232
Linear Formula: C₂₂H₂₄N₂O₈ · xH₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-T3258-5G	5 g	$48.80 1/EA	Add To Favorites
45-T3258-25G	25 g	$76.40 1/EA	Add To Favorites
45-T3258-100G	100 g	$199.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: T3258-25G

Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	Gram-negative bacteria
	Gram-positive bacteria
assay	98.0-102.0% (HPLC)
color	faint yellow to dark yellow
form	powder or crystals
InChI	1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1
InChI key	OFVLGDICTFRJMM-WESIUVDSSA-N
mode of action	protein synthesis \| interferes
Quality Level	200
SMILES string	CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)cccc4[C@@]3(C)O
storage condition	(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
storage temp.	2-8°C

Biochem/physiol Actions:	Mode of Action: Tetracycline passively diffuses through proin channels in the cell membrane, binding to 30S ribosomes and inhibits protein synthesis by preventing access of aminoacyl tRNA to the acceptor site on the mRNA-ribosome complex. It also binds to the bacterial 50S ribosomal subunit, altering the membrane and causing intracellular components to leak from bacterial cells. The inhibitory effects can be reversed by washing, suggesting that it is the reversibly bound antibiotic, and not the irreversibly bound drug, that is responsible for antibacterial action. Mode of Resistance: The effects are inactivated via a loss of cell wall permeability. Antimicrobial spectrum: Includes a wide range of antimicrobial activity against gram-positive and gram-negative bacteria.
General description:	Chemical structure: tetracycline
Other Notes:	Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place
Packaging:	5, 25 g in poly bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P301 + P312 + P330
Hazard Codes	Xn
Risk Statements	22
Safety Statements	22-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	98.0-102.0% (HPLC)
Storage Temp.	2-8°C
UNSPSC	51101500

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