Transferrin human
SIGMA/T3309 - ≥98%
Synonym: Siderophilin, partially saturated
CAS Number: 11096-37-0
EC Number: 234-318-8
MDL Number: MFCD00132442
Product Type: Chemical
| assay | ≥98% |
| biological source | human |
| form | powder |
| impurities | ≤1.0 EU/mg endotoxin |
| Iron content | 300-600 ppm |
| Quality Level | 200  |
| storage temp. | 2-8°C |
| technique(s) | cell culture | stem cell: suitable |
| UniProt accession no. | P02787  |
| Analysis Note: | Purity by agarose electrophoresis. |
| Application: | Transferrin has been used: • in isolation of epidermal stem cells and cell expansion • to study the effect of compound treatment on transferrin uptake • for transferrin uptake and confocal imaging |
| Biochem/physiol Actions: | Transferrin facilitates the transfer of iron to erythron and peripheral tissues. Mutations in this gene is associated with atransferrinemia. Transferrin is required for fetal development. It is non immunogenic and transferrin-conjugated drugs inhibits cardiotoxicity and drug resistance. |
| Biochem/physiol Actions: | Transferrin was shown to promote the proliferation of human lymphocytes. This effect is directly proportional to the level of iron present. |
| General description: | Transferrin is an 80 kDa serum glycoprotein, which has an half-life of 8 to 10 days. The gene is located on human chromosome 3q22.1. Transferrin is expressed in hepatocytes. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Purity | ≥98% |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352202 |