Tylosin solution
SIGMA/T3397 - 8 mg/mL in 0.9% NaCl, 0.1 μm filtered, BioReagent, suitable for cell culture
CAS Number: 74610-55-2
MDL Number: MFCD07783824
Product Type: Chemical
antibiotic activity spectrum | Gram-positive bacteria |
mycoplasma | |
color | colorless to yellow |
concentration | 8 mg/mL in 0.9% NaCl |
form | solution |
impurities | endotoxin, tested |
InChI | 1S/C46H77NO17.C4H6O6/c1-1 |
InChI key | ICVKYYINQHWDLM-KBEWXLTPSA |
mode of action | protein synthesis | interferes |
product line | BioReagent |
Quality Level | 200 ![]() |
SMILES string | O[C@H]([C@@H](O)C(O)=O)C( |
sterility | 0.1 μm filtered |
storage condition | (Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and keep upright to prevent leakage.) |
storage temp. | 2-8°C |
technique(s) | cell culture | mammalian: suitable |
Application: | Tylosin solution has been used as an antimicrobial agent in antibiotic susceptibility minimal inhibitory concentration(MIC) of E. coli and S. aureus isolates. It has also been used as a component of Dulbecco′s modified Eagle′s (DMEM) medium for self-inactivating lentivirus production and skin fibroblast cultivation. |
Biochem/physiol Actions: | Tylosin inhibits bacterial protein synthesis by binding to the large subunit 50S. It is effective against Gram-positive bacteria and mycoplasma and is used in veterinary medicine. It has been used to study implant site abscess prevention in cattle and Mycoplasma gallisepticum and Mycoplasma meleagridis infections. |
General description: | Chemical structure: macrolide |
General description: | Tylosin is a macrolide antibiotic, which comprises of a 16-member lactone ring. This solution is recommended for use at 1 mL/L. |
Other Notes: | Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. |
Packaging: | 20ML |
Preparation Note: | This product was formulated to contain 8 mg/ml tylosin in 0.9% sodium chloride. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-8°C |
UNSPSC | 51101500 |