Toloxatone
SIGMA/T3452 - ≥98% (HPLC), solid
Synonym: 5-
CAS Number: 29218-27-7
Empirical Formula (Hill Notation): C11H13NO3
Molecular Weight: 207.23
EC Number: 249-522-2
MDL Number: MFCD00865391
Linear Formula: C11H13NO3
Product Type: Chemical
| assay | ≥98% (HPLC) |
| form | solid |
| InChI | 1S/C11H13NO3/c1-8-3-2-4-9 |
| InChI key | MXUNKHLAEDCYJL-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | Cc1cccc(c1)N2CC(CO)OC2=O |
| solubility | DMSO: >10 mg/mL |
| storage condition | desiccated |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | Toloxatone is a reversible monoamine oxidase A inhibitor (MAOI) and antidepressant. |
| Biochem/physiol Actions: | Toloxatone is a reversible monoamine oxidase A inhibitor (MAOI) and antidepressant. Toloxatone belongs to the aryloxazolidinones, a relatively new class of reversible monoamine oxidase A inhibitors (MAOI). Studies show that derivatives such as 3-aryloxazolidin-2-one (oxazolidinones), which are regularly used to treat gram positive infections, represent a new class of reversible as well as irreversible inhibitors for MAO-A and MAO-B enzymes that are able to inhibit protein synthesis and also used for neurodegenerative-type pathologies. |
| Packaging: | 10, 50 mg in glass bottle |
| Preparation Note: | Toloxatone is soluble in DMSO at a concentration that is greater than 10 mg/ml. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12161501 |