Advanced Search



Toyocamycin

SIGMA/T3580 - ≥98% (HPLC), from Streptomyces rimosus

Synonym: 4-Aminopyrrolo[2,3-d]pyrimidine-5-carbonitrile 7-(β-D-ribofuranoside); 7-Deaza-7-cyanoadenosine; NSC 63701; NSC 99843; Neuro 000027; Unamycin B; Vengicide

CAS Number: 606-58-6
Empirical Formula (Hill Notation): C12H13N5O4
Molecular Weight: 291.26
MDL Number: MFCD00866513
Linear Formula: C12H13N5O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-T3580-10MG 10 mg
 $152.00
1/EA		 Add To Favorites

 

antibiotic activity spectrum fungi
assay ≥98% (HPLC)
biological source Streptomyces rimosus
form solid
InChI 1S/C12H13N5O4/c13-1-5-2-17(11-7(5)10(14)15-4-16-11)12-9(20)8(19)6(3-18)21-12/h2,4,6,8-9,12,18-20H,3H2,(H2,14,15,16)/t6-,8-,9-,12-/m1/s1
InChI key XOKJUSAYZUAMGJ-WOUKDFQISA-N
mode of action DNA synthesis | interferes
Quality Level 200 
SMILES string Nc1ncnc2n(cc(C#N)c12)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O
solubility aqueous acid: moderately soluble
  DMSO: soluble 0.90-1.10 mg/mL, clear, colorless
  ethanol: moderately soluble
  H2O: moderately soluble
  methanol: moderately soluble
storage temp. 2-8°C
Biochem/physiol Actions: Studies have implicated that toyocamycin blocks the replication of fowl plague virus.
Biochem/physiol Actions: Toyocamycin is a nucleoside- type antibiotic analogue of adenosine, isolated from Streptomyces species. Toyocamycin is an anti-tumor antibiotic with various target activities. Toyocamycin is a potent inhibitor of RNA self-cleavage in mammalian cells. It also inhibits phosphatidylinositol kinase, a cell proliferation regulator. Toyocamycin was also found to inhibit Auxin signaling. Auxins are plant hormones with a crucial role in plant development regulation, and Toyocamycin was found to specifically inhibit auxin-responsive gene expression.
Biochem/physiol Actions: Toyocamycin is a nucleoside-type antibiotic analogue of adenosine, isolated from Streptomyces species. Toyocamycin is an anti-tumor antibiotic with various target inhibitory activities.
Features and Benefits: This compound is featured on the Adenosine Receptors  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Preparation Note: Toyocamycin is soluble in DMSO at 0.90 - 1.10 mg/ml and yields a clear, colorless solution. It is also soluble in acidic solutions and is moderately soluble in water, methanol and ethanol. Solutions prepared in DMSO can be diluted 10-fold in water.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

The following items have been added to your cart:

Choose a favorite list for this item:
Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Year Price Updates

We are currently working diligently to update our website pricing information for the New Year. If you place an order, you will be acknowledged with any corrected pricing. If you'd like the most current information sooner, please don't hesitate to drop us an email or give us a call and we'd be happy to assist. Thank you for your patience while we are updating.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top