Synonym: 2-[(3α,7α,12α-Trihydroxy-24-oxo-5β-cholan-24-yl)amino]ethanesulfonic acid; 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide; Sodium taurocholate hydrate
CAS Number: 345909-26-4
Empirical Formula (Hill Notation): C26H44NNaO7S · xH2O
Molecular Weight: 537.68 (anhydrous basis)
EC Number: 205-653-7
MDL Number: MFCD00150819
Linear Formula: C26H44NNaO7S · xH2O
Product Type: Chemical
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This image depicts SKU: T4009-100G
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This image depicts SKU: T4009-25G
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This image depicts SKU: T4009-1G
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This image depicts SKU: T4009-250MG
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This image depicts SKU: T4009-5G
aggregation number |
4 |
assay |
≥95% (HPLC) |
biological source |
synthetic (organic) |
CMC |
3-11 mM (20-25°C) |
description |
anionic |
form |
powder |
functional group |
sulfonic acid |
InChI |
1S/C26H45NO7S.Na.H2O/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);;1H2/q;+1;/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;;/m1../s1 |
InChI key |
RDAJAQDLEFHVNR-NEMAEHQESA-M |
mol wt |
micellar avg mol wt 2100 |
Quality Level |
200 ![External link](https://krackeler.com/images/sigma/ext-link.gif) |
shipped in |
ambient |
SMILES string |
[Na+].[H]O[H].[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@H](CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(=O)NCCS([O-])(=O)=O |
storage temp. |
room temp |
Application: |
Anionic detergent used for protein solubilization. |
Application: |
Taurocholic acid sodium salt hydrate has been used in a study to assess the adsorption of bile acids and salts to vegetable fibrous tissue. It has also been used in a study to investigate a method for determination of conjugated and unconjugated bile salts in serum and jejunal fluid. |
Biochem/physiol Actions: |
Non-sulfated bile salt, physiological transport substrate for the bile salt export pump/sister of Pgp (BSEP/spgp), Na(+)/taurocholate cotransporter (NTCP) and MRP3 into the hepatic carnalicular. |
General description: |
Taurocholic acid sodium salt hydrate is a bile acid with detergent capabilities. |
Packaging: |
1, 5, 25, 100 g in poly bottle |
Packaging: |
250 mg in poly bottle |
Preparation Note: |
Synthesized from cholic acid |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥95% (HPLC) |
Storage Temp. |
room temp |
UNSPSC |
12161900 |