Anti-Transforming Growth Factor-β2 antibody produced in goat
SIGMA/T4442 - affinity isolated antibody, lyophilized powder
Synonym: Anti-TGF-β2
MDL Number: MFCD03456059
Product Type: Chemical
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| application(s) | research pathology |
| biological source | goat |
| clone | polyclonal |
| conjugate | unconjugated |
| form | lyophilized powder |
| Quality Level | 100  |
| species reactivity | human, pig |
| storage temp. | −20°C |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable |
| neutralization: suitable | |
| western blot: 0.1-0.2 μg/mL | |
| UniProt accession no. | P61812  |
| Application: | Anti-Transforming Growth Factor-β2 antibody can be used in western blotting and ELISA. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Transforming Growth Factor-β 2 (TGF-β 2) is a protein produced by many cells and is found in the highest concentration in mammalian bone and porcine platelets. In body fluids like breast milk, amniotic fluid as well as the aqueous and vitreous humor of the eye, the prominent form exist is Latent TGF-β2. It has a pivotal role in regulating invasion in high-grade gliomas by inducing mesenchymal phenotype and remodeling the extracellular matrix. Anti-Transforming Growth Factor-β2 antibody can be used in neutralization and immunohistochemistry. Goat anti-TGF-β 2 antibody reacts specifically with human and porcine TGF-β 2 and TGF-β 1.2. The product has also shown less than 2% cross-reactivity for TGF-β 1, TGF-β 3 and TGF-β 5. |
| Immunogen: | porcine transforming growth factor-β2. |
| Physical form: | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates. |
| Specificity: | The antibody recognizes TGF-β2 and TGF-β1.2. By immunoblotting (non-reducing conditions) and ELISA, the antibody shows less than 2% cross-reactivity with TGF-β1, TGF-β3, and TGF-β5. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 51111800 |