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Thymidine 5′-monophosphate p-nitrophenyl ester sodium salt

SIGMA/T4510 - ≥98% (HPLC)

Synonym: p-Nitrophenyl-5V-thymidine-monophosphate; p-Nph-5V-TMP

CAS Number: 98179-10-3
Empirical Formula (Hill Notation): C16H18N3O10PNa
Molecular Weight: 466.29
Linear Formula: C16H18N3O10PNa
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-T4510-25MG 25 mg
$112.00
1/EA
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45-T4510-100MG 100 mg
$361.00
1/EA
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45-T4510-250MG 250 mg
$738.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T4510-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T4510-250MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T4510-25MG

 

assay ≥98% (HPLC)
form powder
InChI 1S/C16H18N3O10P.Na.H/c1-9-7-18(16(22)17-15(9)21)14-6-12(20)13(28-14)8-27-30(25,26)29-11-4-2-10(3-5-11)19(23)24;;/h2-5,7,12-14,20H,6,8H2,1H3,(H,25,26)(H,17,21,22);;
InChI key PHNRUCBIIRECII-UHFFFAOYSA-N
Quality Level 200 
SMILES string CC(C(N1)=O)=CN([C@H]2C[C@H](O)[C@@H](COP(O)(OC(C=C3)=CC=C3[N+]([O-])=O)=O)O2)C1=O.[Na]
solubility water: 50 mg/mL
storage temp. −20°C
Application: Thymidine 5′-monophosphate p-nitrophenyl ester sodium salt has been used as a substrate for assessing phosphodiesterase activity. It is also been used as a nucleotide analog in the autotaxin inhibition assay.
Biochem/physiol Actions: Thymidine 5′-monophosphate p-nitrophenyl ester sodium salt is an artificial substrate marker for 5′-nucleotide phosphodiesterase enzyme activity. It is also used as a substrate for autotaxin (ATX, NPP2), which is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (NPP) enzyme family.
Packaging: 25, 100, 250 mg in poly bottle
Substrates: A sensitive chromogenic substrate for venom phosphodiesterase. It is not hydrolyzed by bovine spleen phosphodiesterase.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352204

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