Synonym: 3,3′,4′,5,7-Pentahydroxyflavanone hydrate; Dihydroquercetin hydrate
CAS Number: 24198-97-8 (anhydrous)
Empirical Formula (Hill Notation): C15H12O7 · xH2O
Molecular Weight: 304.25 (anhydrous basis)
MDL Number: MFCD11044454
Linear Formula: C15H12O7 · xH2O
Product Type: Chemical
| assay |
≥90% (HPLC) |
| form |
powder |
| InChI |
1S/C15H12O7.H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;/h1-5,14-19,21H;1H2/t14-,15+;/m0./s1 |
| InChI key |
DNQPGSVMBPSRIR-LDXVYITESA-N |
| Quality Level |
100  |
| SMILES string |
O.O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c3ccc(O)c(O)c3 |
| solubility |
DMSO: 20 mg/mL |
| storage temp. |
−20°C |
| Application: |
(±)-Taxifolin hydrate has been used to evaluate its effects when co-supplemented with trehalose to improve the quality of post-thawed ram semen. It may have been used as a reference standard to analyze the bioactive components of ethanolic extract of P. orientale (POE) using high-performance liquid chromatography (HPLC). |
| Biochem/physiol Actions: |
(±)-Taxifolin exerts various pharmacological properties that include anti-inflammatory, anti-cancer, antiviral, and antimicrobial activities. It displays neuroprotective, hepatoprotective effects, and it also protects against cardiovascular diseases. |
| Biochem/physiol Actions: |
Flavonoid, antioxidant. Inhibits lipogenesis in cancer cells, most likely by targeting fatty acid synthase activity. |
| General description: |
Taxifolin or dihydroquercetin is a naturally occurring secondary metabolic compound found in many plants such as onions, milk thistle, Douglas fir bark, and French maritime pine bark. |
| Other Notes: |
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. T4512.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin. |
| Packaging: |
25, 100 mg in glass bottle |
| Symbol |
 GHS07 |
| Signal word |
Warning |
| Hazard statements |
H302 |
| Hazard Codes |
Xn |
| Risk Statements |
22 |
| Safety Statements |
36 |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥90% (HPLC) |
| Storage Temp. |
−20°C |
| UNSPSC |
12352200 |
