Nα-p-Tosyl-L-arginine methyl ester hydrochloride
SIGMA/T4626
Synonym: TAME hydrochloride
CAS Number: 1784-03-8
Empirical Formula (Hill Notation): C14H22N4O4S · HCl
Molecular Weight: 378.87
EC Number: 217-235-1
MDL Number: MFCD00012578
Linear Formula: H2NC(=NH)NH(CH2)3CH(NHSO2C6H4CH3)CO2CH3 · HCl
Product Type: Chemical
assay | ≥98% (TLC) |
color | white |
form | powder |
InChI | 1S/C14H22N4O4S.ClH/c1-10- |
InChI key | JIQFFACVQXXHMY-YDALLXLXSA |
mp | 145-147 (lit.) |
Quality Level | 200 |
SMILES string | Cl.COC(=O)[C@H](CCCNC(N)= |
storage temp. | −20°C |
technique(s) | ligand binding assay: suitable |
Application: | Nα-p-Tosyl- |
Biochem/physiol Actions: | Nα-p-Tosyl-L-arginine methyl ester (TAME) binds to anaphase-promoting complex (APC) and prevents its activation by Cdc20 and Cdh1. |
Packaging: | 5, 25, 100 g in poly bottle |
Substrates: | Substrate for trypsin, thrombin, plasmin, and other proteases. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (TLC) |
mp | 145-147 (lit.) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |