Terazosin hydrochloride
SIGMA/T4680 - ≥98% (TLC), powder
Synonym: 1-
CAS Number: 63074-08-8
Empirical Formula (Hill Notation): C19H25N5O4 · HCl
Molecular Weight: 423.89
MDL Number: MFCD00467965
Linear Formula: C19H25N5O4 · HCl
Product Type: Chemical
assay | ≥98% (TLC) |
color | white to off-white |
form | powder |
InChI | 1S/C19H25N5O4.ClH/c1-26-1 |
InChI key | IWSWDOUXSCRCKW-UHFFFAOYSA |
originator | Abbott |
Quality Level | 200 ![]() |
SMILES string | Cl[H].COc1cc2nc(nc(N)c2cc |
solubility | ethanol: 4 mg/mL |
H2O: soluble 19.60-20.40 mg/mL, clear, colorless to faintly yellow | |
methanol: 20 mg/mL, clear, colorless |
Application: | Terazosin hydrochloride has been used for orthogonality and similarity analysis using reversed-phase chromatographic studies5. Furthermore, terazosin has also been used for the evaluation of chemometric techniques to determine orthogonality and similarity in chromatographic methods6. |
Biochem/physiol Actions: | α1-adrenoceptor antagonist. |
Features and Benefits: | This compound was developed by Abbott ![]() ![]() |
General description: | Terazosin hydrochloride is used to treat hypertension and benign prostatic hyperplasia (BPH). It is metabolised in the liver. It might be associated with dizziness, headache and asthenia. Terazosin hydrochloride is linked to acute generalized exanthematous pustulosis. |
Packaging: | 250 mg in glass bottle |
Packaging: | 50 mg in poly bottle |
Preparation Note: | Terazosin hydrochloride is soluble in water at 19.60 - 20.40 mg/ml and yields a clear, colorless to faint yellow solution. It is also soluble in ethanol at 4 mg/ml. Furthermore, the product is soluble in methanol at 20 mg/ml, with heat as needed, and yields a clear, colorless solution. |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P301 + P312 + P330 |
Hazard Codes | Xn |
Risk Statements | 22 |
Safety Statements | 26 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (TLC) |
UNSPSC | 12352200 |