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Terazosin hydrochloride

SIGMA/T4680 - ≥98% (TLC), powder

Synonym: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]piperazine hydrochloride

CAS Number: 63074-08-8
Empirical Formula (Hill Notation): C19H25N5O4 · HCl
Molecular Weight: 423.89
MDL Number: MFCD00467965
Linear Formula: C19H25N5O4 · HCl
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-T4680-50MG 50 mg
$211.00
1/EA
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45-T4680-250MG 250 mg
$920.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T4680-250MG

 

assay ≥98% (TLC)
color white to off-white
form powder
InChI 1S/C19H25N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22);1H
InChI key IWSWDOUXSCRCKW-UHFFFAOYSA-N
originator Abbott
Quality Level 200 
SMILES string Cl[H].COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)C4CCCO4
solubility ethanol: 4 mg/mL
  H2O: soluble 19.60-20.40 mg/mL, clear, colorless to faintly yellow
  methanol: 20 mg/mL, clear, colorless
Application: Terazosin hydrochloride has been used for orthogonality and similarity analysis using reversed-phase chromatographic studies5. Furthermore, terazosin has also been used for the evaluation of chemometric techniques to determine orthogonality and similarity in chromatographic methods6.
Biochem/physiol Actions: α1-adrenoceptor antagonist.
Features and Benefits: This compound was developed by Abbott . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
General description: Terazosin hydrochloride is used to treat hypertension and benign prostatic hyperplasia (BPH). It is metabolised in the liver. It might be associated with dizziness, headache and asthenia. Terazosin hydrochloride is linked to acute generalized exanthematous pustulosis.
Packaging: 250 mg in glass bottle
Packaging: 50 mg in poly bottle
Preparation Note: Terazosin hydrochloride is soluble in water at 19.60 - 20.40 mg/ml and yields a clear, colorless to faint yellow solution. It is also soluble in ethanol at 4 mg/ml. Furthermore, the product is soluble in methanol at 20 mg/ml, with heat as needed, and yields a clear, colorless solution.
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Precautionary statements P301 + P312 + P330
Hazard Codes Xn
Risk Statements 22
Safety Statements 26
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (TLC)
UNSPSC 12352200

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