Trandolapril
SIGMA/T4827 - ≥98% (HPLC), white, powder
Synonym: (2S,3aR,7aS)
CAS Number: 87679-37-6
Empirical Formula (Hill Notation): C24H34N2O5
Molecular Weight: 430.54
MDL Number: MFCD00865776
Linear Formula: C24H34N2O5
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white |
form | powder |
InChI | 1S/C24H34N2O5/c1-3-31-24( |
InChI key | VXFJYXUZANRPDJ-WTNASJBWSA |
originator | Abbott |
Quality Level | 100 ![]() |
SMILES string | CCOC(=O)[C@H](CCc1ccccc1) |
solubility | DMSO: ≥20 mg/mL |
Application: | Trandolapril has been used as an angiotensin-converting enzyme (ACE) inhibitor to study its effects on responsiveness of human retinal endothelial cells (HRECs) to vascular endothelial growth factor (VEGF). |
Biochem/physiol Actions: | Studies have reported that trandolapril inhibits atherosclerosis1 and decreases the occurrence of atrial fibrillation2. |
Biochem/physiol Actions: | Trandolapril is an ACE inhibitor. Trandolapril differs from other ACE inhibitors in that it has a longer biological half-life and a high degree of lipophilicity. |
Features and Benefits: | This compound was developed by Abbott ![]() ![]() |
Other Notes: | Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. T4827.pdf ![]() ![]() |
Packaging: | 10, 50 mg in glass bottle |
Preparation Note: | Trandolapril is soluble in DMSO at a concentration that is greater than or equal to 20 mg/ml. |
Symbol | ![]() |
Signal word | Danger |
Hazard statements | H360D |
Precautionary statements | P201 - P280 - P308 + P313 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
UNSPSC | 12352200 |