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Trandolapril

SIGMA/T4827 - ≥98% (HPLC), white, powder

Synonym: (2S,3aR,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid; Mavik

CAS Number: 87679-37-6
Empirical Formula (Hill Notation): C24H34N2O5
Molecular Weight: 430.54
MDL Number: MFCD00865776
Linear Formula: C24H34N2O5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-T4827-10MG 10 mg
 $196.00
1/EA		 Add To Favorites
45-T4827-50MG 50 mg
 $777.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white
form powder
InChI 1S/C24H34N2O5/c1-3-31-24(30)19(14-13-17-9-5-4-6-10-17)25-16(2)22(27)26-20-12-8-7-11-18(20)15-21(26)23(28)29/h4-6,9-10,16,18-21,25H,3,7-8,11-15H2,1-2H3,(H,28,29)/t16-,18+,19-,20-,21-/m0/s1
InChI key VXFJYXUZANRPDJ-WTNASJBWSA-N
originator Abbott
Quality Level 100 
SMILES string CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2C3CCCCC3C[C@H]2C(O)=O
solubility DMSO: ≥20 mg/mL
Application: Trandolapril has been used as an angiotensin-converting enzyme (ACE) inhibitor to study its effects on responsiveness of human retinal endothelial cells (HRECs) to vascular endothelial growth factor (VEGF).
Biochem/physiol Actions: Studies have reported that trandolapril inhibits atherosclerosis1 and decreases the occurrence of atrial fibrillation2.
Biochem/physiol Actions: Trandolapril is an ACE inhibitor.
Biochem/physiol Actions: Trandolapril is an ACE inhibitor. Trandolapril differs from other ACE inhibitors in that it has a longer biological half-life and a high degree of lipophilicity.
Features and Benefits: This compound was developed by Abbott . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 10, 50 mg in glass bottle
Preparation Note: Trandolapril is soluble in DMSO at a concentration that is greater than or equal to 20 mg/ml.
Symbol GHS08  GHS08
Signal word Danger
Hazard statements H360D
Precautionary statements P201 - P280 - P308 + P313
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
UNSPSC 12352200

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