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2-((3-Trifluoromethyl)phenyl)histamine dimaleate

SIGMA/T4951 - ≥98% (HPLC), powder

Synonym: (2-[2-(3-Trifluoromethyl)phenyl)-1H-imidazol-4-yl]ethanamine dimaleate; Compound 39

CAS Number: 162049-83-4
Empirical Formula (Hill Notation): C20H20F3N3O8
Molecular Weight: 487.38
MDL Number: MFCD08277024
Linear Formula: C20H20F3N3O8
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-T4951-5MG 5 mg
 $182.00
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assay ≥98% (HPLC)
color off-white
form powder
InChI 1S/C12H12F3N3.2C4H4O4/c13-12(14,15)9-3-1-2-8(6-9)11-17-7-10(18-11)4-5-16;2*5-3(6)1-2-4(7)8/h1-3,6-7H,4-5,16H2,(H,17,18);2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-
InChI key GGDUVPKRZGATLR-SPIKMXEPSA-N
Quality Level 100 
SMILES string OC(=O)C=C/C(O)=O.OC(=O)C=C/C(O)=O.NCCc1c[nH]c(n1)-c2cccc(c2)C(F)(F)F
solubility H2O: ~20 mg/mL
storage temp. 2-8°C
Application: 2-((3-Trifluoromethyl)phenyl)histamine dimaleate has been used to study the induction of goblet cell secretion in rats3. 2-((3-Trifluoromethyl)phenyl)histamine dimaleate has also been used to study the role of H1 receptor in COX-2 regulation and prostanoid homeostasis in human vascular endothelial cells4.
Biochem/physiol Actions: 2-((3-Trifluoromethyl)phe
Biochem/physiol Actions: Potent and selective H1 histamine receptor agonist.
Features and Benefits: This compound is featured on the Histamine Receptors  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5 mg in glass bottle
Preparation Note: 2-((3-Trifluoromethyl)phenyl)histamine dimaleate is soluble in water at approximately 20 mg/ml.
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352116

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