Tanshinone I
SIGMA/T5330 - ≥98% (HPLC)
Synonym: Tanshinon I; Tanshinone A; Tanshinquinone I
CAS Number: 568-73-0
Empirical Formula (Hill Notation): C18H12O3
Molecular Weight: 276.29
MDL Number: MFCD00210563
Linear Formula: C18H12O3
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: T5330-25MG
This image depicts SKU: T5330-25MG
| application(s) | metabolomics vitamins, nutraceuticals, and natural products |
| assay | ≥98% (HPLC) |
| color | red |
| form | powder |
| InChI | 1S/C18H12O3/c1-9-4-3-5-12 |
| InChI key | AIGAZQPHXLWMOJ-UHFFFAOYSA |
| Quality Level | 200  |
| SMILES string | Cc1coc2-c3ccc4c(C)cccc4c3 |
| solubility | DMSO: 1 mg/mL |
| storage temp. | 2-8°C |
| Application: | Tanshinone 1 has been used:• to test its hematopoiesis effects on human leukemia cell lines and zebrafish xenograft models • to study its anti-cancer effects on two breast cancer cell lines (MCF7 and MDA-MB-23) • as a reference standard to quantify the bioactive component S. miltiorrhiza extract (SME) using high-performance liquid chromatography (HPLC) |
| Biochem/physiol Actions: | Phenanthrenequinone constituent of Chinese medicinal herb Danshen (Salvia miltiorrhiza). Modulates or prevents breast cancer metastasis by regulating adhesion molecules. Anti-inflammatory. |
| Biochem/physiol Actions: | TanshinoneI is extensively studied for its anticancer properties, it was reported to inhibit cancer cell invasion, metastasis, and migration and is a potent antitumor agent. It also displays antibacterial, neuroprotective, memory-enhancing, and cardioprotective activities. |
| General description: | Tanshinone I (Tan I) is a phenolic compound primarily isolated from Danshen. It has an abietane diterpene norditerpenoid o-quinones structure. Tan I have poor water solubility. |
| Packaging: | 25 mg in poly bottle |
| Packaging: | 5 mg in glass bottle |
| Hazard statements | H413 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352205 |